South Africa has received its first batch of Lenacapavir, a six-monthly injectable HIV prevention medicine aimed at improving protection for vulnerable groups. Picture Credit: BBC
By Aisha Zardad
South Africa — South Africa has taken a major step forward in its fight against HIV, receiving its first shipment of Lenacapavir — a new long-acting prevention medicine — with 37,920 doses now in the country.
The Department of Health confirmed the arrival on Tuesday, describing the development as a significant boost to the country’s HIV prevention efforts.
Lenacapavir, administered as an injection every six months, is being introduced as part of a broader shift towards more accessible and people-centred prevention strategies. The approach aims to reduce new infections while strengthening South Africa’s long-term HIV response in alignment with the Global AIDS Strategy for 2026–2030.
“This is part of integrated, differentiated and people-centred HIV prevention services which offer new hope for people who face barriers to existing HIV prevention methods,” the Department said.
Unlike daily prevention options, the six-monthly injection is expected to improve consistency and uptake, particularly among high-risk and vulnerable groups. These include adolescent girls and young women, sex workers, and men who have sex with men — populations that often face barriers to regular access and adherence.
“Lenacapavir is preventive medicine, not a vaccine, considered one of the most exciting HIV prevention advances in years.”
The Department confirmed that the shipment arrived in the country last Thursday, with preparations now underway for a formal national rollout.
Health Minister Dr Aaron Motsoaledi welcomed the development, indicating that the official launch will be led at the highest level.
“This six-monthly injectable has arrived in the country last week Thursday and is expected to expand HIV prevention choices, improve adherence especially amongst the most vulnerable priority groups,” the Department said.
Further details on how the medicine will be distributed will be outlined in a phased implementation plan, expected to be announced in the coming weeks.
The arrival of the initial 37,920 doses marks a critical milestone, introducing a new layer of protection in South Africa’s ongoing battle against HIV — and offering renewed hope for communities most at risk.